| Description |
Open pressure chamber
The open pressure chamber is almost immune to vibrations and movements and, unless they are extremely large, the open system is unaffected by leaks. The pressure controller is contained in a small, lightweight enclosure that can easily be mounted near the micropipette to help reduce dead space. It includes an amplifier, a piezoelectric valve and a pressure transducer. The user supplies fluid-filled microelectrodes, +500 mm Hg pressure source and a -300 mm Hg vacuum source.
Electric potential
Measuring electric potential and pressure simultaneously lets you use potential recording as an additional cue for locating the electrode where visibility is limited, or correlate pressure and potential when this is meaningful. The unique “Set Pressure” mode lets you preset the internal pressure of the microelectrode - select a positive pressure for flushing the tip, or a negative pressure for pulling solution into the tip. By disconnecting the microelectrode holder and attaching the tubing to a manometer, you can check the calibration against a standard.
Built-in alarm
A built-in alarm sounds to indicate maximum pressure. The alarm also sounds when the tip is blocked or electrical continuity is broken (e.g., the microelectrode comes out of the solution, too little filling solution to cover the Ag/AgCl pellet, disconnected ground reference, etc.).
Piezoelectric pressure controller
The piezoelectric pressure controller regulates internal pipette pressure by controlling air flow into and out of a small pressure chamber. A vacuum source is connected on the outlet side of the chamber, and a piezoelectric valve meters air entering the pressurized chamber. The residual volume of the pressure chamber includes the micropipette, the connecting tubing and the pressure transducer on the outlet side of the piezoelectric valve. The 900A accurately controls and adjusts the pressure in the chamber to match pressures applied externally to the microelectrode tip. The response time of the piezoelectric valve is 0.5?ms from fully closed to fully open. Overall system response time depends largely on the amount of residual volume in the tubing. When this volume is small, the system responds very rapidly (typically 10 milliseconds).
Minimize dead space
The lightweight pressure controller pod may be mounted close to the microelectrode using small-bore tubing, to minimize system dead space.
Note
Microelectrode holders MEH6RF and MEH6SF for 1.0?mm O.D. capillary glass included. (1.2, 1.5 and 2.0?mm also available - please specify when ordering.)
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| Specifications |
Additional information not available |
| Manuals and Resources |
Instruction Manual
900A-IM-0897.pdf |
| References |
Have you seen a reference to this product in a published paper? If so, email your contact information and the citation and we will send you a free gift!
T. Kuwaki, T. Ishii, K. Ju, M. Yanagisawa, Y. Fukuda. "Blood pressure of endotheline-3 (-/-) knockout mice and endothelin A receptor null (-/-) knockout mice under anaesthesia." Clinical Science 103. 2002: 485-525.
J.L. Lucitti, K. Tobita, B. B. Keller. "Arterial hemodynamics and mechanical properties after circulatory intervention in the chick embryo." J of Experimental Biology 208. 2005: 1877-1885.
G. Luippold, S. Schneider, V. Vallon, H. Osswald, B. Muhbauer. "Postglomerular vasoconstriction induced by dopamine D3 receptor activation in anesthetized rats." Am J Physiol Renal Physiol 278. 2000: F570-F575.
M. Yoshigi, G.D. Knott, B.B. Keller. "Lumped parameter estimation for the embryonic chick vascular system: a time-domain approach using MLAB." Computer Methods and Programs in Biomedicine 63. 2000: 29-41.
V. Vallon, J.R. Schwark, K. Richter, M. Hropot. "Role of Na+/H+ exchanger NHE3 in nephron function: micropuncture studies with S3226, an inhibitor of NHE." Am J Physiol Renal Physiol 278. 2000: F375-F379.
K. Tobita, B.B. Keller. "Maturation of end-systolic stress-strain relations in chick embryonic myocardium." Am J Physiol Heart Circ Physiol 279. 2000: H216-H224.
R.R. Myers, B.L. Rydevik, H.M. Heckman, H.C. Powell. "Proximodistal Gradient in Endoneurial Fluid Pressure." Experimental Neurology 102. 1988: 368-370.
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| Ordering Information |
To place an order for this product, please contact the appropriate WPI office or distributor.
Customers can order direct from our China office:
WPI China
Address: Rm.20A, No.8 Dong Fang Rd, Liang Feng Building, Lu Jia Zui Financial District, Shanghai PRC
Phone:+86 21 68885517
Fax:+86 21 68885537
Code:200120
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| Accessories |
There are no accessories for this product. |
| Application Notes |
No Application Notes available for this product at this time. |
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