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Linear Stimulus Isolator

/images/big705.jpg * Replicates a programmed waveform of any shape or polarity
* Ideally suited for data acquisition and stimulator generators
* Contains 17 alkaline 9V batteries
* Designed for Neuroscience & Muscle applications
Description Features
All WPI stimulus isolators are designed to supply constant current because current threshold (not voltage) is the most quantitatively reproducible parameter for stimulation of nerve and muscle. Model A395 dispenses current reproducibly from its Output terminals; the amplitude being determined by the selected current RANGE and the input voltage. Current amplitude is “constant”, that is, load resistance independent, provided that the I x R (load) product does not exceed the available battery supply voltage. An audible alarm (the compliance alarm) will sound if I x R reaches this limit. Model A395 D can generate a voltage of 70 volts or more across its OUTPUT terminals. Thus, the user can be sure that the amplitude of the current will be as dialed as long as the voltage drop accross the load (stimulus electrode path) does not reach the magnitude of the supply voltage. The compliance alarm would then be heard. The user would then know that (a) too much current was dialed for a given load or (b) inter-electrode resistance was too high or the electrode circuit path was open.

Output current
Model A395 generates an output current of arbitrary (user-defined) wave shape; DC, AC, pulse, and combinations thereof. Battery operated, and photoelectrically-isolated from the input voltage drive, the instrument regenerates output currents which are linearly proportional to the analog voltage waveforms provided by your D/A converter or signal generator. The A395 is ideally suited for data acquisition and stimulator generators. It can be easily daisy-chained for mutiple channel requirements.

Current Delivery
A 10 V input produces the maximum output current for the current range selected, i.e., 100 µA, 1?mA, or 10?mA. Front panel controls allow DC current to be generated. Externally applied signals can be superimposed simultaneously (DC offset). Warning lamps indicate open circuit or excessive current conditions.

Digital Meter
Measures DC or average output current.

Overload Lamps
Indicate when output voltage has reached positive or negative compliance voltage limit.
Specifications
OUTPUT CURRENT, Imax 3 ranges: 100?A, 1 mA, and 10 mA
OUTPUT VOLTAGE RANGE ± 70 V
OUTPUT BANDWIDTH 10 kHz (measured across 1KMΩ load R)
INPUT RESISTANCE > 20 MMΩ
INPUT VOLTAGE @ Imax ± 10 volts
INPUT/OUTPUT LINEARITY ERROR < 0.5%
RISE, FALL TIME 26 ?s @ 10 KMΩ
POWER: Model A395D 17 alkaline 9 V batteries
POWER: Model A395R 17 rechargeable NiMH 9 V batteries
DIMENSIONS 6.5 x 4 x 3.5 in. (16 x 10 x 9 cm)
SHIPPING WEIGHT 4 lb (1.8 kg)
Manuals and Resources Instruction Manual A395-IM-092608.pdf
References P. Grafe, V. Schaffer, F. Rucker. "Kinetics of ATP release following compression injury of a peripheral nerve trunk." Purinergic Signalling 2. 2006: 527-536.

S. Braner, R.B. Stein, E. Fernandez, Y. Aoyagi, R.A. Normann. "Long-term stimulation and recording with a penetrating microelectrode array in cat sciatic nerve." Biomedical Engineering 51. 2004: 146-157.

P. Lang, W. Sippel, S. Schmidbauer, D. Irnich, P. Grafe. "Functional Evidence for P2X Receptors in Isolated Human Vagus Nerve." Anesthesiology 2003. 99: 232-235.

E.D. Zonnevijille, N.N. Somia, g.Perez Abadia, R.W. Stremel, C.J. Maldonado, P.M.N. Werker, M. Kon, J.H. Barker. "Sequential Segmental Neuromuscular Stimulation Reduces Fatigue and Imrproves Perfusion in dynamic Gracilolasty." Ann Plast Surg 45. 2000: 292-297.
Ordering Information To place an order for this product, please contact the appropriate WPI office or distributor.

Customers can order direct from our China office:
WPI China
Address: Rm.20A, No.8 Dong Fang Rd, Liang Feng Building, Lu Jia Zui Financial District, Shanghai PRC
Phone:+86 21 68885517
Fax:+86 21 68885537
Code:200120
Accessories 3468 - Dual Rack Mount Kit
3469 - Single Rack Mount Kit
Application Notes Application Notes No Application Notes available for this product at this time.
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